Two sample MR report
PLGRKT_Dendritic Cell (DC) against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | -0.0752961 | 0.0688857 | 0.3357826 |
| Weighted median | 6 | -0.0411068 | 0.0109628 | 0.0001771 |
| Inverse variance weighted | 6 | -0.0399170 | 0.0086711 | 0.0000042 |
| Simple mode | 6 | -0.0430577 | 0.0141352 | 0.0285501 |
| Weighted mode | 6 | -0.0432520 | 0.0149775 | 0.0342743 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.3537111 | 4 | 0.9860882 |
| Inverse variance weighted | 0.6217334 | 5 | 0.9869866 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0204786 | 0.0395563 | 0.6319761 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001325 | 0 | TRUE | 0.2774638 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
